Identifying Missing Biosynthesis Enzymes of Plant Natural Products

Abstract

Elucidating plant-specialized biosynthetic pathways has always constituted a laborious task, notably for natural products with high pharmaceutical values. Here, we discuss emerging omics-based strategies that facilitate the identification of genes from these complex metabolic pathways, paving the way to engineered supplies of these compounds through synthetic biology approaches.

Keywords: RNA-seq; coexpression network; gene identification; specialized metabolites; whole genome sequencing.