Automated Insulin Delivery in Children with Type 1 Diabetes

Endocrinol Metab Clin North Am. 2020 Mar;49(1):157-166. doi: 10.1016/j.ecl.2019.10.012.

Abstract

The advent of insulin pump therapy marked an important milestone in diabetes treatment in the past few decades and has become the tipping point for the development of automated insulin delivery systems (AID). Standalone insulin pump systems have evolved over the course of years and have been replaced by modern high-technology insulin pumps with continuous glucose monitor interface allowing real-time insulin dose adjustment to optimize treatment. This review summarizes evidence from AID studies conducted in children with type 1 diabetes and discusses the outlook for future generation AID systems from a pediatric treatment perspective.

Keywords: Children; Diabetes; Insulin; Insulin pump.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adolescent
  • Automation / instrumentation
  • Blood Glucose / analysis
  • Blood Glucose Self-Monitoring / instrumentation
  • Blood Glucose Self-Monitoring / trends
  • Child
  • Child, Preschool
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / drug therapy*
  • Humans
  • Insulin / administration & dosage*
  • Insulin Infusion Systems* / trends
  • Inventions / trends

Substances

  • Blood Glucose
  • Insulin