Long-term Puberty Suppression for a Nonbinary Teenager

Pediatrics. 2020 Feb;145(2):e20191606. doi: 10.1542/peds.2019-1606.

Abstract

Many transgender and gender-diverse people have a gender identity that does not conform to the binary categories of male or female; they have a nonbinary gender. Some nonbinary individuals are most comfortable with an androgynous gender expression. For those who have not yet fully progressed through puberty, puberty suppression with gonadotrophin-releasing hormone agonists can support an androgynous appearance. Although such treatment is shown to ameliorate the gender dysphoria and serious mental health issues commonly seen in transgender and gender-diverse young people, long-term use of puberty-suppressing medications carries physical health risks and raises various ethical dilemmas. In this Ethics Rounds, we analyze a case that raised issues about prolonged pubertal suppression for a patient with a nonbinary gender.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anxiety / drug therapy
  • Bioethical Issues
  • Bone Density / drug effects
  • Clinical Decision-Making / ethics
  • Drug Administration Schedule
  • Ethics, Medical
  • Gender Dysphoria / drug therapy*
  • Gender Dysphoria / psychology
  • Hip Fractures / etiology
  • Humans
  • Informed Consent By Minors / ethics*
  • Parental Consent / ethics*
  • Personal Autonomy
  • Puberty / drug effects*
  • Selective Estrogen Receptor Modulators / therapeutic use*
  • Sexual and Gender Minorities / psychology*

Substances

  • Selective Estrogen Receptor Modulators