Application of Rigidity-Controlled Supramolecular Affinity Materials for the Gravimetric Detection of Hazardous and Illicit Compounds

Isabella Pyka; Dimitrij Ryvlin; Siegfried R Waldvogel

doi:10.1002/cplu.201600296

Application of Rigidity-Controlled Supramolecular Affinity Materials for the Gravimetric Detection of Hazardous and Illicit Compounds

Chempluschem. 2016 Sep;81(9):926-929. doi: 10.1002/cplu.201600296. Epub 2016 Jul 29.

Authors

Isabella Pyka¹, Dimitrij Ryvlin¹, Siegfried R Waldvogel¹

Affiliation

¹ Institute of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, 55128, Mainz, Germany.

PMID: 31968793
DOI: 10.1002/cplu.201600296

Abstract

The combination of an (-)-isosteviol-derived building block and 9,9'-spirobifluorene or tetraphenylmethane generated highly potent new affinity materials for the detection of volatile organic compounds (VOCs). Comparison of their affinity behaviour with different core structures showed remarkable influence on selectivity and sensitivity due to structural rigidity and their pre-organization. Their unique supramolecular properties were investigated in an affinity assay using high fundamental frequency quartz crystal microbalances.

Keywords: 9,9’-spirobifluorene; affinity materials; molecular recognition; supramolecular chemistry; tetraphenylmethane.