Intravenous immunoglobulin in resistant livedoid vasculopathy: Analysis of a case series

Dermatol Ther. 2020 Mar;33(2):e13229. doi: 10.1111/dth.13229. Epub 2020 Feb 4.

Abstract

We report a retrospective analysis the efficacy of high-dose intravenous immunoglobulins on 9 patients with Livedoid vasculopathy for whom resistant to immunosuppressants plus anticoagulants or could not be prescribed. Intravenous immunoglobulins were used 2 g/kg per month in these patients. The treatment induced stabilization of the disease and all patients demonstrated improvement with IVIg. Complete and partial clinical response was achieved in 6 and 3 patients respectively.

Keywords: intravenous immunoglobuline; livedoid vasculopathy; therapy-systemic.

MeSH terms

  • Anticoagulants
  • Humans
  • Immunoglobulins, Intravenous
  • Livedo Reticularis* / diagnosis
  • Livedo Reticularis* / drug therapy
  • Retrospective Studies
  • Vascular Diseases*

Substances

  • Anticoagulants
  • Immunoglobulins, Intravenous