Public Health Program for Decreasing Risk for Ebola Virus Disease Resurgence from Survivors of the 2013-2016 Outbreak, Guinea

Emerg Infect Dis. 2020 Feb;26(2):206-211. doi: 10.3201/eid2602.191235.

Abstract

At the end of the 2013-2016 Ebola virus disease outbreak in Guinea, we implemented an alert system for early detection of Ebola resurgence among survivors. Survivors were asked to report health alerts in their household and provide body fluid specimens for laboratory testing. During April-September 2016, a total of 1,075 (88%) of 1,215 survivors participated in the system; follow up occurred at a median of 16 months after discharge (interquartile range 14-18 months). Of these, 784 acted as focal points and reported 1,136 alerts (including 4 deaths among survivors). A total of 372 (91%) of 408 eligible survivors had >1 semen specimen tested; of 817 semen specimens, 5 samples from 4 survivors were positive up to 512 days after discharge. No lochia (0/7) or breast milk (0/69) specimens tested positive. Our findings underscore the importance of long-term monitoring of survivors' semen samples in an Ebola-affected country.

Keywords: Ebola; Ebola virus disease; Guinea; West Africa; resurgence; surveillance; survivors; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Body Fluids / virology
  • Child
  • Child, Preschool
  • Disease Outbreaks / prevention & control
  • Ebolavirus / isolation & purification*
  • Family Characteristics
  • Female
  • Guinea / epidemiology
  • Hemorrhagic Fever, Ebola / epidemiology*
  • Hemorrhagic Fever, Ebola / prevention & control
  • Hemorrhagic Fever, Ebola / virology
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Public Health
  • Recurrence
  • Semen / virology
  • Survivors
  • Young Adult