Kidney Transplantation in Transgender Patients

Curr Urol Rep. 2020 Jan 18;21(1):1. doi: 10.1007/s11934-020-0953-x.

Abstract

Purpose of review: Kidney transplantation and gender affirmation treatments are becoming increasingly more prevalent due to advances in technology. However, there is a paucity of data regarding kidney transplantation in transgender patients. Interesting considerations must be made in this patient population, since there are many hormonal interactions with kidney function and the transplantation process.

Recent findings: The diagnosis of estimated glomerular filtration rate (eGFR), preoperative assessment/counseling, decreased testosterone levels in a transgender male to female patient, increased estrogen/progesterone in a female to male patient, and drug side effects all have important and unique implications for kidney transplant recipients. Kidney transplantation can be safely and effectively managed in transgender patients with special considerations in eGFR calculations, mental health/lifestyle counseling, and drug interactions.

Keywords: Estrogen; Kidney transplantation; Patient counseling; Progesterone; Testosterone; Transgender; eGFR.

Publication types

  • Review

MeSH terms

  • Glomerular Filtration Rate
  • Humans
  • Kidney Failure, Chronic / physiopathology
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation*
  • Transgender Persons*
  • Transsexualism / drug therapy
  • Transsexualism / metabolism
  • Transsexualism / surgery