Simulated in vitro infant gastrointestinal digestion of yak milk fat globules: A comparison with cow milk fat globules

Jie Luo; Lu Liu; Tianshu Liu; Qingwu Shen; Chengguo Liu; Hui Zhou; Fazheng Ren

doi:10.1016/j.foodchem.2020.126160

Simulated in vitro infant gastrointestinal digestion of yak milk fat globules: A comparison with cow milk fat globules

Food Chem. 2020 Jun 1:314:126160. doi: 10.1016/j.foodchem.2020.126160. Epub 2020 Jan 7.

Authors

Jie Luo¹, Lu Liu², Tianshu Liu², Qingwu Shen³, Chengguo Liu⁴, Hui Zhou⁴, Fazheng Ren⁵

Affiliations

¹ College of Food Science and Technology, Hunan Agricultural University, Changsha 410114, China; Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Government, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China. Electronic address: luojie@hunau.edu.cn.
² Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Government, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
³ College of Food Science and Technology, Hunan Agricultural University, Changsha 410114, China. Electronic address: sqw@hunau.edu.cn.
⁴ College of Food Science and Technology, Hunan Agricultural University, Changsha 410114, China.
⁵ Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Government, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China; Beijing Laboratory of Food Quality and Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China. Electronic address: renfazheng@cau.edu.cn.

PMID: 31958749
DOI: 10.1016/j.foodchem.2020.126160

Abstract

Lipolysis products released during digestion exert positive metabolic impacts on the nutrition of newborns. However, the lipolysis behavior of yak milk lipids during digestion remains unknown. In this study, the simulated in vitro infant gastrointestinal digestion of cow, yak and standardized yak milk fat globules the same size as those from cow milk (Cow MF, Yak MF and Yak SMF) were compared. Although Cow MF showed a higher lipolysis rate at the beginning of gastric digestion, Yak MF and Yak SMF exhibited a higher lipolysis level during later gastrointestinal digestion. Higher hydrolysis efficiency of yak milk lipids was due to their lipid properties, including their composition and structure. Furthermore, yak milk lipids released more unsaturated fatty acids than Cow MF throughout digestion. This study highlights the crucial role of lipid characteristics in the efficient digestion of milk lipids and provides new insight for the design of yak milk infant diets.

Keywords: In vitro gastrointestinal digestion; Infant; Lipolysis; Yak milk fat globule.

Publication types

Comparative Study

MeSH terms

Animals
Cattle
Digestion*
Fatty Acids, Unsaturated / pharmacokinetics
Female
Glycolipids / chemistry
Glycolipids / pharmacokinetics*
Glycoproteins / chemistry
Glycoproteins / pharmacokinetics*
Humans
Hydrolysis
Infant
Infant, Newborn
Lipid Droplets
Lipids / chemistry
Lipolysis
Milk / chemistry*

Substances

Fatty Acids, Unsaturated
Glycolipids
Glycoproteins
Lipids
milk fat globule