Epidermolysis Bullosa Simplex Keratinocytes Show Disturbed Mitochondrial Positioning and Activity

J Invest Dermatol. 2020 Jul;140(7):1438-1442.e5. doi: 10.1016/j.jid.2019.10.023. Epub 2020 Jan 18.

Authors

Alyssa Vetter¹, Kristin Jahn¹, Jamal-Eddine Bouameur¹, Dimitra Kiritsi², Thomas M Magin³

Affiliations

¹ Institute of Biology, Division of Cell and Developmental Biology, University of Leipzig, Leipzig, Germany.
² Department of Dermatology, Faculty of Medicine, Medical Center- University of Freiburg, Freiburg, Germany.
³ Institute of Biology, Division of Cell and Developmental Biology, University of Leipzig, Leipzig, Germany. Electronic address: thomas.magin@uni-leipzig.de.

PMID: 31958432
DOI: 10.1016/j.jid.2019.10.023

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Line
Cell Nucleus / metabolism
Cytoplasm / metabolism
Cytoskeleton / metabolism
Epidermolysis Bullosa Simplex / metabolism*
Humans
Keratinocytes / metabolism
Keratinocytes / pathology*
Keratins / metabolism*
Mitochondria / pathology*
Mutation
Oxidation-Reduction
Oxygen / metabolism
Reactive Oxygen Species / metabolism
Signal Transduction

Substances

Reactive Oxygen Species
Keratins
Oxygen