Data on the recovery of glycinergic neurons after spinal cord injury in lampreys

Silvia María Valle-Maroto; Antón Barreiro-Iglesias; Blanca Fernández-López; María Celina Rodicio

doi:10.1016/j.dib.2019.105092

Data on the recovery of glycinergic neurons after spinal cord injury in lampreys

Data Brief. 2020 Jan 3:28:105092. doi: 10.1016/j.dib.2019.105092. eCollection 2020 Feb.

Authors

Silvia María Valle-Maroto¹, Antón Barreiro-Iglesias¹, Blanca Fernández-López¹, María Celina Rodicio¹

Affiliation

¹ Department of Functional Biology, CIBUS, Faculty of Biology, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.

Abstract

We used immunohistochemical methods to quantify changes in the number of glycine-immunoreactive neurons of the dorsomedial, lateral and cerebrospinal fluid contacting cell populations of the spinal cord of larval sea lampreys after a complete spinal cord injury. The data presented here are quantifications of the number of glycine-immunoreactive neurons located in the rostral and caudal stumps of the spinal cord and the corresponding statistical analyses. These data show that, glycine immunoreactivity is lost in glycinergic neurons immediately after injury and that the number of glycine-immunoreactive neurons is recovered in the following two weeks. These data are useful for researchers investigating determinants that underlie the spontaneous recovery of locomotion following spinal injuries in regenerating animal models, and for analysing the role of glycinergic neurons in spinal cord repair after an injury.

Keywords: Central nervous system repair; Glycine; Neuronal regeneration; Neurotransmitter; Spinal cord injury.