Central pontine myelinolysis following rapid correction of hyponatremia in an alcoholic

Am J Kidney Dis. 1988 Dec;12(6):531-3. doi: 10.1016/s0272-6386(88)80106-9.

Abstract

An alcoholic patient presented with profound hyponatremia of uncertain etiology. Despite partial correction of hyponatremia within 24 hours, central pontine myelinolysis (CPM) ensued and the patient subsequently died. The optimal rate of correction of severe, symptomatic hyponatremia has not yet been elucidated.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alcoholism / complications*
  • Demyelinating Diseases / etiology*
  • Demyelinating Diseases / pathology
  • Humans
  • Hyponatremia / etiology
  • Hyponatremia / therapy*
  • Male
  • Pons* / pathology
  • Time Factors