Topical niacinamide does not stimulate hair growth based on the existing body of evidence

J E Oblong; A W Peplow; S M Hartman; M G Davis

doi:10.1111/ics.12599

Topical niacinamide does not stimulate hair growth based on the existing body of evidence

Int J Cosmet Sci. 2020 Apr;42(2):217-219. doi: 10.1111/ics.12599.

Authors

J E Oblong¹, A W Peplow¹, S M Hartman², M G Davis¹

Affiliations

¹ Beauty Technology Division, The Procter & Gamble Company, Cincinnati, OH, USA.
² Global Biosciences Division, The Procter & Gamble Company, Cincinnati, OH, USA.

PMID: 31955438
DOI: 10.1111/ics.12599

Abstract

Niacinamide has been suggested to impact hair biology via stimulation of VEGF synthesis. Testing in an in vitro VEGF synthesis assay, it was found that niacinamide cannot stimulate VEGF synthesis across a broad dose-response range.

Publication types

Letter

MeSH terms

Administration, Topical
Dose-Response Relationship, Drug
Hair / drug effects*
Hair / growth & development
Humans
Niacinamide / administration & dosage*
Niacinamide / pharmacology
Vascular Endothelial Growth Factor A / biosynthesis

Substances

Vascular Endothelial Growth Factor A
Niacinamide