Recent advances in electrospun nanofibers for some biomedical applications

Eur J Pharm Sci. 2020 Mar 1:144:105224. doi: 10.1016/j.ejps.2020.105224. Epub 2020 Jan 15.

Abstract

Nanofibers provide multiple merits for the delivery of many therapeutic agents with versatile biomedical applications. With the fast recent advancement in nanotechnology, nanofibers could be easily fabricated with tunable morphologies and release profiles. Here, we review the most recent approaches in the fabrication of electrospun nanofibers incorporating some natural ingredients for their wound healing potential. In addition, electrospun nanofibers for treatment of skin carcinoma and delivery of different growth factors for tissue regeneration will also be highlighted in this review. Nanofibers incorporating different active therapeutical agents are very promising drug delivery platforms.

Keywords: Antimicrobial peptides; Electrospinning; Growth factors; Herbal extracts; Nanofibers; Skin cancer; Wound healing.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents
  • Drug Delivery Systems / methods*
  • Humans
  • Intercellular Signaling Peptides and Proteins
  • Nanofibers*
  • Nanotechnology
  • Skin Neoplasms
  • Wound Healing

Substances

  • Anti-Infective Agents
  • Intercellular Signaling Peptides and Proteins