Using MetaboAnalyst 4.0 for Metabolomics Data Analysis, Interpretation, and Integration with Other Omics Data

Jasmine Chong; Jianguo Xia

doi:10.1007/978-1-0716-0239-3_17

Using MetaboAnalyst 4.0 for Metabolomics Data Analysis, Interpretation, and Integration with Other Omics Data

Methods Mol Biol. 2020:2104:337-360. doi: 10.1007/978-1-0716-0239-3_17.

Authors

Jasmine Chong¹, Jianguo Xia^{2

3

4

5}

Affiliations

¹ Institute of Parasitology, McGill University, Montreal, QC, Canada.
² Institute of Parasitology, McGill University, Montreal, QC, Canada. jeff.xia@mcgill.ca.
³ Department of Animal Science, McGill University, Montreal, QC, Canada. jeff.xia@mcgill.ca.
⁴ Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada. jeff.xia@mcgill.ca.
⁵ Department of Human Genetics, McGill University, Montreal, QC, Canada. jeff.xia@mcgill.ca.

PMID: 31953825
DOI: 10.1007/978-1-0716-0239-3_17

Abstract

MetaboAnalyst ( www.metaboanalyst.ca ) is an easy-to-use, comprehensive web-based tool, freely available for metabolomics data processing, statistical analysis, functional interpretation, as well as integration with other omics data. This chapter first provides an introductory overview to the current MetaboAnalyst (version 4.0) with regards to its underlying design concepts and user interface structure. Subsequent sections describe three common metabolomics data analysis workflows covering targeted metabolomics, untargeted metabolomics, and multi-omics data integration.

Keywords: Enrichment analysis; Metabolic pathway analysis; Multi-omics integration; Multivariate statistics; Web server.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Computational Biology / methods*
Data Analysis*
Databases, Factual
Metabolic Networks and Pathways
Metabolomics* / statistics & numerical data
Software*
User-Computer Interface
Web Browser
Workflow

Grants and funding

U01 CA235493/CA/NCI NIH HHS/United States