Stacked Bt Proteins Pose No New Risks to Nontarget Arthropods

Trends Biotechnol. 2020 Mar;38(3):234-236. doi: 10.1016/j.tibtech.2019.12.001. Epub 2020 Jan 14.

Abstract

Concerns have been raised that multiple insecticidal proteins produced by genetically engineered (GE) crops may interact unexpectedly and pose new threats to biodiversity and nontarget organisms. We reviewed the literature to assess whether this concern is justified and whether the current regulatory framework needs to be adapted to address this concern.

Keywords: Cry proteins; environmental risk assessment; genetically modified crops; nontarget effects; pyramids; synergistic effects.

Publication types

  • Review

MeSH terms

  • Animals
  • Arthropods / drug effects*
  • Bacillus thuringiensis Toxins / genetics*
  • Bacillus thuringiensis Toxins / toxicity
  • Crops, Agricultural / genetics*
  • Ecotoxicology
  • Endotoxins / genetics*
  • Endotoxins / toxicity
  • Hemolysin Proteins / genetics*
  • Hemolysin Proteins / toxicity
  • Plants, Genetically Modified / genetics*

Substances

  • Bacillus thuringiensis Toxins
  • Endotoxins
  • Hemolysin Proteins
  • insecticidal crystal protein, Bacillus Thuringiensis