Nerves of Steel: How the Gut Nervous System Promotes a Strong Barrier

Cameron H Flayer; Caroline L Sokol

doi:10.1016/j.cell.2019.12.021

Nerves of Steel: How the Gut Nervous System Promotes a Strong Barrier

Cell. 2020 Jan 9;180(1):15-17. doi: 10.1016/j.cell.2019.12.021.

Authors

Cameron H Flayer¹, Caroline L Sokol²

Affiliations

¹ Center for Immunology & Inflammatory Diseases, Division of Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
² Center for Immunology & Inflammatory Diseases, Division of Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: clsokol@mgh.harvard.edu.

Abstract

In this issue of Cell, Jarret et al., Lai et al., and Matheis et al. demonstrate the extensive interplay between the nervous system and immune and epithelial cells of the gut to orchestrate host defense in homeostasis and following Salmonella infection.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Enteric Nervous System*
Gastrointestinal Microbiome*
Immunity, Mucosal
Interleukin-18
Steel

Substances

Interleukin-18
Steel

Abstract

Publication types

MeSH terms

Substances

Grants and funding