Whole Food-Based Approaches to Modulating Gut Microbiota and Associated Diseases

Annu Rev Food Sci Technol. 2020 Mar 25:11:119-143. doi: 10.1146/annurev-food-111519-014337. Epub 2020 Jan 17.

Abstract

Intake of whole foods, such as fruits and vegetables, may confer health benefits to the host. The beneficial effects of fruits and vegetables were mainly attributed to their richness in polyphenols and microbiota-accessible carbohydrates (MACs). Components in fruits and vegetables modulate composition and associated functions of the gut microbiota, whereas gut microbiota can transform components in fruits and vegetables to produce metabolites that are bioactive and important for health. The progression of multiple diseases, such as obesity and inflammatory bowel disease, is associated with diet and gut microbiota. Although the exact causality between these diseases and specific members of gut microbiota has not been well characterized, accumulating evidence supported the role of fruits and vegetables in modulating gut microbiota and decreasing the risks of microbiota-associated diseases. This review summarizes the latest findings on the effects of whole fruits and vegetables on gut microbiota and associated diseases.

Keywords: fruits and vegetables; gut microbiota; microbiota-accessible carbohydrates; polyphenols; whole foods.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Diet
  • Food*
  • Gastrointestinal Microbiome*
  • Humans