Aims: To evaluate the efficacy of exercise-based interventions and mind-body therapies on quality of life, menopausal symptoms, and depression among Asian perimenopausal women.
Design: A systematic review, meta-analysis, and synthesis without meta-analysis (SWiM).
Data sources: Six electronic databases were systematically searched: PubMed, CINAHL, Embase, PsycINFO, Scopus, and ProQuest.
Review methods: The point of inception of each database to 15 November 2018 were systematically searched. A meta-analysis and SWiM were used to present the results. Review Manager 5.3 and The Cochrane Risk of Bias tool were used for meta-analyses and assessing of risk of bias, respectively.
Results: In all, 23 studies were reviewed. Significant effects in exercise-based interventions and mind-body therapies were found for quality of life, menopausal symptoms, and depression but not for hot flashes. Limitations of this review include insufficient blinding of participants and/or researchers found in most of the included studies and high levels of heterogeneity in the meta-analyses. Evidence found in this review is to be interpreted with caution.
Conclusion: Healthcare professionals can consider exercise-based interventions or mind-body therapies to manage menopausal symptoms. Future trials of good quality can examine the cost-effectiveness and optimal intervention duration. Intervention effects on specific menopausal symptoms such as sleeplessness in Asia can be examined in future.
Impact: Exercise-based interventions and mind-body therapies suggest effectiveness on quality of life, menopausal symptoms, and depression among Asian perimenopausal women. Exercise-based interventions and mind-body therapies improve quality of life, menopausal symptoms, and depression but not hot flashes. Long-term exercise-based interventions is effective in managing depression. Due to varied limitations in the review and included studies, firm conclusions cannot be reached. Healthcare professionals in Asia can consider implementing exercise-based interventions and mind-body therapies for symptomatic perimenopausal Asian women.
目的: 评价运动干预和身心疗法对亚洲围绝经期妇女生活质量、更年期症状和抑郁情绪的影响。 设计: 开展系统评估、荟萃分析以及不包括荟萃分析的综合汇总(SWiM)。 数据来源: 通过6大电子数据库:PubMed、CINAHL、Embase、PsycINFO、Scopus和ProQuest展开系统性检索。 评估方法: 对各个数据库自建立之初到2018年11月15日期间所发表的文献进行系统性检索。采用荟萃分析和SWiM方法来展示检索结果。使用Review Manager 5.3和Cochrane偏倚风险工具分别进行荟萃分析和偏倚风险评估。 结果: 共对23项研究进行了评估。结果显示,运动干预和身心疗法对生活质量、更年期症状和抑郁情绪具有显著影响,但对热潮红并无效果。本项评估的局限性包括在大多数纳入研究中发现参与者和/或研究人员的盲法试验不够充分,以及荟萃分析中存在高度异质性。因此,在解释本项评估中所发现的证据时需格外谨慎。 结论: 医疗服务人员可考虑采用运动干预或身心疗法来控制更年期症状。对于成本效益和最佳干预时间,未来可通过开展更多高质量试验予以检验确定。针对亚洲妇女特定更年期症状(如失眠)的干预效果将在未来得到检验。 影响: 运动干预和身心疗法对亚洲围绝经期妇女的生活质量、更年期症状和抑郁情绪具有显著影响。运动干预和身心疗法有助于改善生活质量、更年期症状和抑郁情绪,但对热潮红并无效果。长期运动干预可有效治疗抑郁症。由于评估和纳入研究存在各种局限性,目前无法得出明确的结论。亚洲地区的医疗服务人员可考虑对有症状的围绝经期妇女实施运动干预和身心疗法。.
Keywords: Asia; depression; exercise; menopausal symptom; meta-analysis; mind-body therapy; nurse; perimenopause; quality of life; systematic review.
© 2020 John Wiley & Sons Ltd.