Primary cardiac lymphoma mimicking atrial myxoma in an HIV and EBV-positive patient: a case report

Guanghui Gong; Ting Lin; Keda Yang

Primary cardiac lymphoma mimicking atrial myxoma in an HIV and EBV-positive patient: a case report

Int J Clin Exp Pathol. 2018 Nov 1;11(11):5497-5501. eCollection 2018.

Authors

Guanghui Gong^{1

2

3}, Ting Lin^{4

5}, Keda Yang^{1

2}

Affiliations

¹ Department of Pathology, Xiangya Hospital, Central South University Changsha, Hunan, People's Republic of China.
² Department of Pathology, School of Basic Medical Science, Central South University Changsha, Hunan, People's Republic of China.
³ Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University Changsha, People's Republic of China.
⁴ Hunan Provincial Key Laboratory for The Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Traditional Chinese Medicine Changsha, People's Republic of China.
⁵ Hunan Provincial Key Discipline of Chinese Head and Neck Science Changsha, People's Republic of China.

PMID: 31949636
PMCID: PMC6963007

Abstract

Primary cardiac lymphoma (PCL) is an extremely rare neoplasm arising from the heart (and/or pericardium) and should be distinguished from the secondary involvement of lymphomas from other parts of the body or other malignant tumors originating from the heart. In the present report, we present the case of a 40-year-old male infected with HIV (human immunodeficiency virus) and EBV (Epstein-Barr virus) suffering from palpitation, dyspnea for a month, and in whom echocardiography showed a mass in the right atrium suggesting atrial myxoma. A surgical excision of the lesion was performed, but, unexpectedly, a diagnosis of diffuse large B-cell lymphoma was made according to the microscopic features and immunohistochemical studies.

Keywords: EBV; HIV; Primary cardiac lymphoma; atrial myxoma.

Publication types

Case Reports