1 Department of Anesthesiology, University of Groningen, University Medical Center Groningen, The Netherlands Department of Critical Care, University of Groningen, University Medical Center Groningen, The Netherlands, and Department of Internal Medicine, University of Groningen, University Medical Center Groningen, The Netherlands Department of Critical Care, University of Groningen, University Medical Center Groningen, The Netherlands Department of Intensive Care, University of Maastricht, Maastricht University Medical Center+, Maastricht, The Netherlands, and SICS Study Group, Department of Critical Care, University of Groningen, University Medical Center Groningen, The Netherlands.