A turn-on luminescence probe for highly selective detection of an anthrax biomarker

Luminescence. 2020 Jun;35(4):601-607. doi: 10.1002/bio.3764. Epub 2020 Jan 8.

Abstract

Highly selective detection of Bacillus anthrax spores has attracted worldwide attention because Bacillus anthrax spores not only are harmful to the health of human beings and animals, but also can be used as biological warfare agents. Here, we report a simple platform by mixing EuCl3 ·6H2 O and sodium polyacrylate in aqueous solution and further investigate its luminescence response towards Bacillus anthrax biomarker dipicolinic acid (DPA) as a turn-on luminescence probe. Importantly, our probe has good sensitivity, lower detection limit, excellent selectivity as well as great anti-interference ability due to the great luminescence enhancement of Eu3+ . Moreover, a test paper is constructed to realize the purpose of portable detection. These results indicate that our probe is an excellent candidate for sensing DPA.

Keywords: DPA; anthrax biomarker; lanthanide; luminescence; turn-on.

MeSH terms

  • Bacillus anthracis / chemistry*
  • Biomarkers / analysis
  • Biosensing Techniques*
  • Humans
  • Luminescent Agents / chemistry*
  • Luminescent Measurements
  • Picolinic Acids / analysis*
  • Spores, Bacterial / chemistry

Substances

  • Biomarkers
  • Luminescent Agents
  • Picolinic Acids
  • dipicolinic acid