What potential is there for LSD1 inhibitors to reach approval for AML?

Expert Opin Emerg Drugs. 2019 Dec;24(4):205-212. doi: 10.1080/14728214.2019.1694001.
No abstract available

Keywords: LSD1 inhibitor; acute myeloid leukemia; clinical trial; epigenetic.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Clinical Trials as Topic
  • Enzyme Inhibitors / therapeutic use*
  • Histone Demethylases / antagonists & inhibitors*
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / metabolism*

Substances

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Histone Demethylases
  • KDM1A protein, human