Hypertriglyceridemia triggered acute pancreatitis in pregnancy - diagnostic approach, management and follow-up care

Lipids Health Dis. 2020 Jan 4;19(1):2. doi: 10.1186/s12944-019-1180-7.

Abstract

Acute pancreatitis is a pregnancy complication potentially lethal for both the mother and fetus, occurring most frequently in the third trimester or early postpartum. Hypertriglyceridemia may be the cause of important disease in pregnant patients. Patients with triglyceride levels exceeding 1000 mg/dL are at increased risk of developing severe pancreatitis. Diagnostic criteria and management protocols are not specific for pancreatitis complicating pregnancy. Other causes of acute abdominal pain must be considered in the differential diagnosis. Decision-making in the obstetric context is challenging and bears potential legal implications. Pre-pregnancy preventive measures and prenatal antilipemic treatment are mandatory in high risk patients.

Keywords: Acute pancreatitis; Hypertriglyceridemia; Pregnancy.

Publication types

  • Review

MeSH terms

  • Acute Disease / epidemiology
  • Acute Disease / therapy*
  • Aftercare
  • Female
  • Humans
  • Hypertriglyceridemia / complications
  • Hypertriglyceridemia / diagnosis
  • Hypertriglyceridemia / drug therapy*
  • Hypertriglyceridemia / physiopathology
  • Hypolipidemic Agents / therapeutic use
  • Pancreatitis / diagnosis
  • Pancreatitis / drug therapy*
  • Pancreatitis / etiology
  • Pancreatitis / physiopathology
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / drug therapy*
  • Pregnancy Complications / physiopathology
  • Triglycerides / blood

Substances

  • Hypolipidemic Agents
  • Triglycerides