Enhancement of blurry retinal image based on non-uniform contrast stretching and intensity transfer

Med Biol Eng Comput. 2020 Mar;58(3):483-496. doi: 10.1007/s11517-019-02106-7. Epub 2020 Jan 2.

Abstract

Proper contrast and sufficient illuminance are important in clearly identifying the retinal structures, while the required quality cannot always be guaranteed due to major reasons like acquisition process and diseases. To ensure the effectiveness of enhancement, two solutions are developed for blurry retinal images with sufficient illuminance and insufficient illuminance, respectively. The proposed contrast stretching and intensity transfer are main steps in both of the two solutions. The contrast stretching is based on base-intensity removal and non-uniform addition. We assume that a base-intensity exists in an image, which mainly supports the basic illuminance but has less contribution to texture information. The base-intensity is estimated by the constrained Gaussian function and then removed. The non-uniform addition using compressed Gamma map is further developed to improve the contrast. Additionally, an effective intensity transfer strategy is introduced, which can provide required illuminance for a single channel after contrast stretching. The color correction can be achieved if the intensity transfer is performed on three channels. Results show that the proposed solutions can effectively improve the contrast and illuminance, and good visual perception for quality degraded retinal images is obtained. Illustration of contrast stretching based on a signal colour channel.

Keywords: Contrast stretching; Enhancement; Intensity transfer; Retinal image.

MeSH terms

  • Color
  • Contrast Media / chemistry*
  • Humans
  • Image Enhancement*
  • Models, Biological
  • Retina / diagnostic imaging*

Substances

  • Contrast Media