Successful management of fibrosing mediastinitis with severe vascular compromise: Report of two cases and literature review

Franklin Argueta; David Villafuerte; Jose Castaneda-Nerio; Jay Peters; Carlos Restrepo

doi:10.1016/j.rmcr.2019.100987

Successful management of fibrosing mediastinitis with severe vascular compromise: Report of two cases and literature review

Respir Med Case Rep. 2019 Dec 14:29:100987. doi: 10.1016/j.rmcr.2019.100987. eCollection 2020.

Authors

Franklin Argueta¹, David Villafuerte^{2

3}, Jose Castaneda-Nerio^{2

3}, Jay Peters^{2

3}, Carlos Restrepo⁴

Affiliations

¹ Department of Internal Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
² Division of Pulmonary Diseases and Critical Care Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
³ Division of Pulmonary Diseases & Critical Care Medicine, South Texas Veterans Health Care System, San Antonio, TX, USA.
⁴ Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Abstract

Fibrosing mediastinitis is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum. This fibrosis can result in compression of intrathoracic structures including the pulmonary vasculature leading to clinical symptoms and complications like pulmonary hypertension. Here, we present two cases of young patients with fibrosing mediastinitis complicated by pulmonary artery stenosis requiring medical and endovascular management with excellent results.

Keywords: Fibrosing mediastinits; Pulmonary artery stenosis; Pulmonary hypertension.

Publication types

Case Reports