Patients with Parkinson's Disease and Myasthenia Gravis-A Report of Three New Cases and Review of the Literature

Medicina (Kaunas). 2019 Dec 23;56(1):5. doi: 10.3390/medicina56010005.

Abstract

Neurodegenerative diseases such as Parkinson's disease (PD)have increasing incidence, due to lifespan expansion. The association between PD and Myasthenia Gravis (MG) is uncommon, and so far, since 1987, 26 cases have been reported. We report here a series of three new cases, two men and one woman with this peculiar combination of conditions, identified in the Neurology Department of Colentina Clinical Hospital. In this article, the pathogenesis of MG in patients with PD is discussed, along with a literature review regarding the co-occurrence of these two neurological diseases.

Keywords: Myasthenia gravis; Parkinson disease; case report; co-occurrence.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Dyskinesias / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myasthenia Gravis / diagnosis*
  • Myasthenia Gravis / physiopathology
  • Parkinson Disease / diagnosis*
  • Parkinson Disease / physiopathology