Simultaneous Time-of-Flight PET/MR Identifies the Hepatic 90Y-Resin Distribution After Radioembolization

Clin Nucl Med. 2020 Feb;45(2):e92-e93. doi: 10.1097/RLU.0000000000002850.

Abstract

A 61-year-old woman with multiple hepatic metastases from uterus cervical cancer received Y radioembolization. The simultaneous time-of-flight (TOF) PET/MR clearly identified the untreated tumor parts on the posttherapeutic Y internal pair-production imaging. After another boosted Y injection, the metastatic hepatic tumors were well covered. The follow-up PET/MR revealed tumor shrinkage. The one-stop-shop TOF PET/MR provided useful follow-up information in patients receiving Y radioembolization.

Publication types

  • Case Reports

MeSH terms

  • Embolization, Therapeutic*
  • Female
  • Humans
  • Kinetics
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / metabolism
  • Liver Neoplasms / secondary
  • Magnetic Resonance Imaging*
  • Microspheres
  • Middle Aged
  • Multimodal Imaging
  • Positron-Emission Tomography*
  • Resins, Synthetic / chemistry
  • Uterine Cervical Neoplasms / pathology*
  • Yttrium Radioisotopes / chemistry
  • Yttrium Radioisotopes / metabolism*
  • Yttrium Radioisotopes / therapeutic use*

Substances

  • Resins, Synthetic
  • Yttrium Radioisotopes
  • Yttrium-90