We experimentally study interactions between two microwave fields mediated by 3-level transmon artificial atom with two-photon processes. The transmon has good selection rule, preventing one-photon transition, but allowing two-photon transition from ground state(0) to 2nd excited state(2). By pumping a control tone in resonance to the transition between 1st(1) and 2nd excited state(2), we control the one-photon transparency for 0 to 1 transition and two-photon transparency for 0 to 2 transition. The results are explained by the Autler-Townes splitting induced by the control microwave. In addition, two possible microwave amplification processes involving two-photon processes are also studied. The 4-wave mixing scheme increases the transmission by 3% while 2-photon optical pumping produces a 11% narrowband increment. All these phenomena can be operated with control and probe tones in a narrow band.