Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma

Yash Dilip Nilak; Anjumara Nilak; Salim Shafeek; Dr Zbigniew Rudzki; Joanne Chapman

doi:10.1016/j.radcr.2019.10.018

Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma

Radiol Case Rep. 2019 Nov 28;15(2):156-160. doi: 10.1016/j.radcr.2019.10.018. eCollection 2020 Feb.

Authors

Yash Dilip Nilak¹, Anjumara Nilak², Salim Shafeek^{3

4}, Dr Zbigniew Rudzki^{5

6}, Joanne Chapman⁵

Affiliations

¹ Department of Medicine, Worcester Royal Hospital, Worcester WR5 1DD, UK.
² Department of Radiology, Worcester Royal Hospital Worcester, WR5 1DD, UK.
³ Worcestershire Acute Hospitals NHS trust, Worcester, WR5 1DD, UK.
⁴ Hon Sen Lecturer in Clinical Haematology, University of Birmingham, Birmingham, UK.
⁵ Heartlands Hospital, Birmingham, B9 5SS, UK.
⁶ Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.

Abstract

Benign xanthomatous pseudotumors are rare, mass forming lesions composed of lipid laden histiocytes and tumor necrosis following chemotherapy. We present a rare case of young 36 year old male with primary mediastinal Hodgkin's lymphoma who developed xanthomatous pseudotumor mimicking relapse at the site of original disease on positron emission tomography. This scenario places emphasis on histologic confirmation of suspected treatment failure or relapse.

Keywords: Histiocyte-rich pseudotumor; Nodular sclerosing Hodgkin's lymphoma; PET; Tumor necrosis.

Publication types

Case Reports