Immunity to Influenza Infection in Humans

Cold Spring Harb Perspect Med. 2021 Mar 1;11(3):a038729. doi: 10.1101/cshperspect.a038729.

Abstract

This review discusses the human immune responses to influenza infection with some insights from studies using animal models, such as experimental infection of mice. Recent technological advances in the study of human immune responses have greatly added to our knowledge of the infection and immune responses, and therefore much of the focus is on recent studies that have moved the field forward. We consider the complexity of the adaptive response generated by many sequential encounters through infection and vaccination.

Publication types

  • Review

MeSH terms

  • Adaptive Immunity*
  • Age Factors
  • Animals
  • Antibodies, Viral / immunology*
  • CD8-Positive T-Lymphocytes / immunology
  • Disease Models, Animal
  • Humans
  • Influenza Vaccines / immunology*
  • Influenza, Human / immunology
  • Influenza, Human / prevention & control*
  • Mice

Substances

  • Antibodies, Viral
  • Influenza Vaccines