Aureimonas altamirensis masquerading as Brucella spp. in a blood culture from a 68-year-old male with cancer

Diagn Microbiol Infect Dis. 2020 Mar;96(3):114957. doi: 10.1016/j.diagmicrobio.2019.114957. Epub 2019 Dec 5.

Abstract

Staphylococcus epidermidis and a Gram negative bacillus (GNB) were isolated in blood cultures from a 68-year-old male with cancer. The GNB was suspicious for Brucella spp., but was identified using 16S rDNA sequencing as Aureimonas altamirensis. The complexity of the identification is described in this case study.

Keywords: 16S sequencing; Aureimonas; Brucella blood culture; Cancer; MALDI-TOF-MS; Next-generation sequencing; PCR; Whole-genome sequencing.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Alphaproteobacteria / drug effects
  • Alphaproteobacteria / isolation & purification*
  • Anti-Infective Agents / pharmacology
  • Bacterial Infections / diagnosis*
  • Bacterial Infections / microbiology
  • Blood Culture*
  • Brucella
  • Genome, Bacterial
  • Humans
  • Male
  • Neoplasms / complications
  • Neoplasms / microbiology
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Whole Genome Sequencing

Substances

  • Anti-Infective Agents
  • RNA, Ribosomal, 16S

Supplementary concepts

  • Aureimonas altamirensis