[Intravenous thrombolysis after reversion of acenocoumarol anticoagulation. Report of one case]

Rev Med Chil. 2019 Jul;147(7):932-934. doi: 10.4067/S0034-98872019000700932.
[Article in Spanish]

Abstract

We report an 89-year-old male under oral anticoagulant therapy with a therapeutic international normalized ratio, presenting at the emergency room with right side hemiparesis and aphasia. Neuroimaging was compatible with an acute middle cerebral artery ischemic stroke. Anticoagulation was reverted with the use of four factor prothrombin complex, followed by thrombolysis with alteplase, with a favorable evolution, returning to his basal functional status.

Publication types

  • Case Reports

MeSH terms

  • Acenocoumarol / administration & dosage
  • Acenocoumarol / adverse effects*
  • Administration, Intravenous
  • Aged, 80 and over
  • Amlodipine / administration & dosage
  • Amlodipine / adverse effects*
  • Humans
  • Infarction, Middle Cerebral Artery / drug therapy*
  • Infarction, Middle Cerebral Artery / etiology
  • Male
  • Metformin / administration & dosage
  • Metformin / adverse effects*
  • Prothrombin / administration & dosage*
  • Stroke / drug therapy*
  • Stroke / etiology
  • Thrombolytic Therapy / methods*
  • Tomography, X-Ray Computed

Substances

  • Amlodipine
  • Prothrombin
  • Metformin
  • Acenocoumarol