Microstructural features of lyophilized adipose - A new concept to estimate the metabolic symptoms for obese patients

Med Hypotheses. 2020 Mar:136:109526. doi: 10.1016/j.mehy.2019.109526. Epub 2019 Dec 11.

Abstract

The aim of this study was to investigate the distribution of different morphological features in different layers of lyophilized adipose tissue. In this work the scanning electron microscopy (SEM) was adopted for investigation of lyophilized adipose tissue taken from obese patients. The adipose tissue was taken from subcutaneous (SAT), preperitoneal (PAT) and visceral (VAT) layers of adipose tissue. The obtained results of the main microstructural features provided information about morphological features of subcutaneous, preperitoneal and visceral layers in obese people. The obtained SEM results possibly could be used for the estimation of metabolic symptoms and prediction different diseases. The SEM method was never used before to investigate morphology of SAT, PAT and VAT layers of lyophilized human adipose tissue.

Publication types

  • Letter

MeSH terms

  • Adipose Tissue / ultrastructure*
  • Female
  • Freeze Drying*
  • Humans
  • Intra-Abdominal Fat / physiopathology*
  • Intra-Abdominal Fat / ultrastructure
  • Male
  • Metabolic Syndrome / complications
  • Metabolic Syndrome / diagnosis
  • Metabolic Syndrome / physiopathology*
  • Microscopy, Electron, Scanning
  • Obesity / complications
  • Obesity / diagnosis
  • Obesity / physiopathology*
  • Subcutaneous Fat / physiopathology*
  • Subcutaneous Fat / ultrastructure