Increased cytotoxic potential of CD8⁺ T cells in immune thrombocytopenia

Br J Haematol. 2020 Mar;188(5):e72-e76. doi: 10.1111/bjh.16334. Epub 2019 Dec 18.

Authors

John R Vrbensky¹, Donald M Arnold^{1

2}, John G Kelton^{1

2}, James W Smith¹, Anushka M Jaffer², Mark Larché¹, Rumi Clare^{1

2}, Nikola Ivetic¹, Ishac Nazy^{1

2}

Affiliations

¹ Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
² McMaster Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada.

PMID: 31850531
DOI: 10.1111/bjh.16334

No abstract available

Keywords: CD107a; CD8+ T cells; autoantibodies; immune thrombocytopenia; platelets.

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Autoantibodies / immunology
CD8-Positive T-Lymphocytes / immunology*
CD8-Positive T-Lymphocytes / pathology
Female
Humans
Male
Middle Aged
Purpura, Thrombocytopenic, Idiopathic / immunology*

Substances

Autoantibodies

Grants and funding