Expression quantitative trait locus (eQTL) analysis is a powerful method to understand the association between genetic variant and gene expression; it also has potential impact for the study of transcription medicine for human complex disease. In the past two decades, the researchers focus on studying the eQTL, while more and more evidence shows that the regulatory genetic variants locating noncoding region have strong effect for the gene expression. More and more researchers working on eQTL analysis realize the importance of other types of QTLs beyond eQTL. In this chapter, we will explore some QTLs beyond eQTLs that show the regulatory association with eQTLs and explain the underlying link among these types of QTLs.
Keywords: Association mapping; Gene expression; Molecular trait; eQTL.