Polyphenols, Antioxidant, Antibacterial, and Biofilm Inhibitory Activities of Peel and Pulp of Citrus medica L., Citrus bergamia, and Citrus medica cv. Salò Cultivated in Southern Italy

Molecules. 2019 Dec 13;24(24):4577. doi: 10.3390/molecules24244577.

Abstract

The aim of this paper was to study the polyphenols of peel and pulp of three Citrus taxa-Citrus medica, Citrus bergamia, and Citrus medica cv. Salò-cultivated in the Cosenza province, Southern Italy, and to evaluate their antioxidant and antibacterial activity, performed against Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, and Pectobacterium carotovorum. Furthermore, we assessed the inhibitory effect of the extracts on bacterial capacity to form biofilm, and on the metabolic activity of the cells present therein. The results indicated that such extracts could find new potential applications in the field of natural antioxidant and anti-bacterial agents in pharmaceutics, agriculture, and food fields.

Keywords: Citrus bergamia; Citrus medica; Citrus medica cv. Salò; antibacterial activity; biofilm; polyphenols.

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Antioxidants / chemistry*
  • Antioxidants / pharmacology
  • Biofilms / drug effects*
  • Citrus / chemistry*
  • Escherichia coli / drug effects
  • Escherichia coli / physiology
  • Listeria monocytogenes / drug effects
  • Listeria monocytogenes / physiology
  • Microbial Sensitivity Tests
  • Pectobacterium carotovorum / drug effects
  • Pectobacterium carotovorum / physiology
  • Plant Extracts / chemistry
  • Polyphenols / chemistry*
  • Polyphenols / pharmacology
  • Pseudomonas aeruginosa / drug effects
  • Pseudomonas aeruginosa / physiology
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / physiology

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Plant Extracts
  • Polyphenols