Two new cephalochromin derivative from the Alternaria sp. ZG22

Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-Qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; Chang-Ri Han

doi:10.1080/14786419.2019.1700248

Two new cephalochromin derivative from the Alternaria sp. ZG22

Nat Prod Res. 2021 Oct;35(20):3370-3375. doi: 10.1080/14786419.2019.1700248. Epub 2019 Dec 14.

Authors

Xin-Ming Song^{1

2}, Xue-Ming Zhou^{1

2}, Ya-Ling Li^{1

2}, Li-Bing Huang^{1

2}, Cai-Cui Chen^{1

2}, Yan Gao^{1

2}, Lin He^{1

2}, Xiao-Qun Mao^{1

2}, Bing Chen^{1

2}, Jing-Wen Liu^{1

2}, Hui-Jie Liu^{1

2}, Xiao-Ping Song^{1

2}, Chang-Ri Han^{1

3}

Affiliations

¹ Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou, P. R. China.
² Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, P. R. China.
³ Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province, School of Chemical and Material Engineering, Hainan Vocational University of Science and Technology, Haikou, P. R. China.

PMID: 31841031
DOI: 10.1080/14786419.2019.1700248

Abstract

Two new cephalochromin derivatives, prenylcephalochromin A (1), prenylcephalochromin B (2), along with cephalochromin (3) were isolated from the Alternaria sp. ZG22 obtained from a Dasymaschalon rostratum collected from the Hainan. The structures of two new compounds were elucidated by comprehensive spectroscopic methods. Compounds 1-3 showed α-glucosidase inhibitory activity.

Keywords: Alternaria sp.; cephalochromin derivatives; α-glucosidase inhibitory activity.

MeSH terms

Alternaria*
Annonaceae*
Cephalosporins
Molecular Structure

Substances

Cephalosporins
cephalochromin