The Leeds hand transplant programme: Review of the laboratory management of the first six cases

Brendan Clark; Clive Carter; Daniel J Wilks; Mark Lobb; Pamela Hughes; Richard Baker; Simon P J Kay

doi:10.1111/iji.12466

The Leeds hand transplant programme: Review of the laboratory management of the first six cases

Int J Immunogenet. 2020 Feb;47(1):28-33. doi: 10.1111/iji.12466. Epub 2019 Dec 15.

Authors

Brendan Clark¹, Clive Carter¹, Daniel J Wilks², Mark Lobb¹, Pamela Hughes¹, Richard Baker³, Simon P J Kay²

Affiliations

¹ Departments of Transplant Immunology, Leeds Teaching Hospitals, Leeds, UK.
² Departments of Plastic and Reconstructive Surgery, Leeds Teaching Hospitals, Leeds, UK.
³ Departments of Renal Medicine, Leeds Teaching Hospitals, Leeds, UK.

PMID: 31840432
DOI: 10.1111/iji.12466

Abstract

The UK hand transplantation programme is hosted by the Department of Plastic and Reconstructive Surgery at Leeds Teaching Hospitals under the leadership of Professor Simon Kay. Since programme launch in 2013, ten procedures in six individuals have been performed involving unilateral or bilateral transplants. The multi-disciplinary team that delivers the programme includes the transplant immunology service. The laboratory experience in programme support is reported here.

Keywords: HLA; antibody; hand; immunophenotype; post-transplant; transplant.

Publication types

Case Reports

MeSH terms

Alemtuzumab / pharmacology
Antibodies
Graft Rejection / immunology*
Graft Survival / immunology*
HLA Antigens / immunology*
Hand Transplantation* / methods
Hand Transplantation* / rehabilitation
Humans
Immunization
Immunophenotyping
Transplants / immunology

Substances

Antibodies
HLA Antigens
Alemtuzumab