Agonist-independent GPCR activity and receptor-instructed axonal projection in the mouse olfactory system

Hirofumi Nishizumi; Hitoshi Sakano

doi:10.4155/fmc-2019-0178

Agonist-independent GPCR activity and receptor-instructed axonal projection in the mouse olfactory system

Future Med Chem. 2019 Dec;11(24):3091-3096. doi: 10.4155/fmc-2019-0178.

Authors

Hirofumi Nishizumi¹, Hitoshi Sakano¹

Affiliation

¹ Department of Brain Function, School of Medical Sciences, University of Fukui, Matsuoka, Fukui 910-1193, Japan.

PMID: 31838900
DOI: 10.4155/fmc-2019-0178

No abstract available

Keywords: G-protein coupled receptors; axon targeting; baseline activity; cAMP; olfactory sensory neurons; olfactory system; spontaneous structural transition.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Axons / metabolism*
Axons / ultrastructure
Mice
Mice, Knockout
Mice, Transgenic
Neurons, Afferent / metabolism
Neurons, Afferent / ultrastructure
Olfactory Pathways / cytology*
Olfactory Pathways / metabolism
Receptors, Odorant / genetics
Receptors, Odorant / metabolism*

Substances

Receptors, Odorant