Provocative angiography for lower gastrointestinal bleeding

Jpn J Radiol. 2020 Mar;38(3):248-255. doi: 10.1007/s11604-019-00909-0. Epub 2019 Dec 13.

Abstract

Purpose: This study evaluated the results of provocative angiography performed to identify the site of hemorrhage in lower gastrointestinal bleeding to enable transcatheter arterial embolization.

Materials and methods: The subjects of this study were 11 patients with acute lower gastrointestinal bleeding who underwent provocative angiography, after contrast agent extravasation could not be identified during conventional angiography. One patient underwent provocative angiography twice, making 12 cases of provocative angiography that were analyzed in this study. Urokinase was used in all cases. Heparin was administered in 2 cases, nicardipine in 3 cases, and alprostadil and isosorbide in 1 case each.

Results: Contrast agent extravasation as a result of provocative angiography was observed in 6/12 cases (50%). Selective transcatheter arterial embolization was performed in all 6 cases in which extravasation was apparent, and it was technically successful in all six. Clinical success was achieved in 5 (83.3%) of the 6 cases in which technical success was achieved after provocative angiography.

Conclusion: Provocative angiography enabled the site of lower gastrointestinal bleeding to be identified in 6 of 12 cases (50.0%) when it could not be identified by conventional angiography, and in all 6 cases hemostasis was effectively achieved by embolization.

Keywords: Diverticulum; Embolization; Gastrointestinal bleeding; Pharmacoangiography; Provocative angiography.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angiography / methods*
  • Embolization, Therapeutic / methods*
  • Extravasation of Diagnostic and Therapeutic Materials / complications
  • Extravasation of Diagnostic and Therapeutic Materials / diagnostic imaging
  • Extravasation of Diagnostic and Therapeutic Materials / therapy
  • Female
  • Gastrointestinal Hemorrhage / complications
  • Gastrointestinal Hemorrhage / diagnostic imaging*
  • Gastrointestinal Hemorrhage / therapy*
  • Gastrointestinal Tract / diagnostic imaging
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Urokinase-Type Plasminogen Activator / administration & dosage*

Substances

  • Urokinase-Type Plasminogen Activator