Air2Liquid Method for Selective, Sensitive Detection of Gas-Phase Organophosphates

ACS Sens. 2020 Jan 24;5(1):13-18. doi: 10.1021/acssensors.9b01624. Epub 2019 Dec 20.

Abstract

Environmental hazards typically are encountered in the gaseous phase; however, selective sensing modalities for identifying and quantitating compounds of interest in an inexpensive, pseudo-real-time format are severely lacking. Here, we present a novel proof-of-concept that combines an Air2Liquid sampler in conjunction with an oil-in-water microfluidic assay for detection of organophosphates. We believe this proof-of-concept will enable development of a new platform technology for semivolatile detection that we have demonstrated to detect 50 pmoles (2 ppb) of neurotoxic organophosphates.

Keywords: gas sensor; microfluidic assay; organophosphate; selective sensor; semi-volatile detection.

Publication types

  • Letter
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biosensing Techniques / methods*
  • Gases / chemistry*
  • Organophosphates / metabolism*

Substances

  • Gases
  • Organophosphates