16-Deethylindanomycin (A83094A), a novel pyrrole-ether antibiotic produced by a strain of Streptomyces setonii. Taxonomy, fermentation, isolation and characterization

S H Larsen; L D Boeck; F P Mertz; J W Paschal; J L Occolowitz

doi:10.7164/antibiotics.41.1170

16-Deethylindanomycin (A83094A), a novel pyrrole-ether antibiotic produced by a strain of Streptomyces setonii. Taxonomy, fermentation, isolation and characterization

J Antibiot (Tokyo). 1988 Sep;41(9):1170-7. doi: 10.7164/antibiotics.41.1170.

Authors

S H Larsen¹, L D Boeck, F P Mertz, J W Paschal, J L Occolowitz

Affiliation

¹ Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.

PMID: 3182398
DOI: 10.7164/antibiotics.41.1170

Abstract

16-Deethylindanomycin (A83094A) is a novel pyrrole-ether antibiotic produced by a strain of Streptomyces setonii. The antibiotic, which is structurally similar to indanomycin (X-14547A), is active in vitro against Gram-positive bacteria as well as coccidia.

MeSH terms

Animals
Anti-Bacterial Agents / biosynthesis
Anti-Bacterial Agents / isolation & purification*
Coccidia / drug effects
Fermentation
Gram-Positive Bacteria / drug effects
Indenes / biosynthesis
Indenes / isolation & purification
Indenes / pharmacology
Mice
Pyrans / biosynthesis
Pyrans / isolation & purification
Pyrans / pharmacology
Streptomyces / classification
Streptomyces / metabolism*

Substances

Anti-Bacterial Agents
Indenes
Pyrans
16-deethylindanomycin