Novel ferulic acid and benzophenone derivatives from the flower buds of Syzygium aromaticum

Nat Prod Res. 2021 Oct;35(19):3301-3306. doi: 10.1080/14786419.2019.1698570. Epub 2019 Dec 10.

Abstract

Phytochemical investigation of clove resulted in the isolation of two new natural compounds, a ferulic acid derivative, sabrinic acid (1) and a benzophenone derivative (2) together with two known compounds kaempferol-3,5-dimethyl ether (3) and 4-methyl benzoic acid (4). Compounds 3 and 4 were isolated for the first time from the genus Syzygium. The structures of compounds were elucidated through modern spectroscopic techniques including 1D and 2D NMR spectroscopy.

Keywords: 4; 4′-diacetoxybezophenone; Syzygium aromaticum; cloves; ferulic acid derivative; sabrinic acid.

MeSH terms

  • Benzophenones / chemistry*
  • Benzophenones / isolation & purification
  • Coumaric Acids / chemistry*
  • Coumaric Acids / isolation & purification
  • Flowers / chemistry
  • Molecular Structure
  • Syzygium* / chemistry

Substances

  • Benzophenones
  • Coumaric Acids
  • ferulic acid