Prospective cohort study to investigate the burden and transmission of acute gastroenteritis in care homes: epidemiological results

BMJ Open. 2019 Dec 8;9(12):e033239. doi: 10.1136/bmjopen-2019-033239.

Abstract

Objectives: To estimate the incidence of gastroenteritis in individuals in care homes.

Design: Prospective cohort study.

Setting: Five participating care homes in North West England, UK.

Participants: Residents and staff present at the five study care homes between 15 August 2017 and 30 May 2019 (n=268).

Outcome measures: We calculated incidence rates for all gastroenteritis cases per 1000 person-years at risk and per 1000 bed-days at risk. We also calculated the incidence rate of gastroenteritis outbreaks per 100 care homes per year.

Results: In total 45 cases were reported during the surveillance period, equating to 133.7 cases per 1000 person-years at risk. In residents the incidence rate was 0.62 cases per 1000 bed-days. We observed seven outbreaks in all care homes included in surveillance, a rate of 76.4 outbreaks per 100 care homes per year. 15 stool samples were tested; three were positive for norovirus, no other pathogens were detected.

Conclusions: We found that surveillance of infectious gastroenteritis disease in care homes based on outbreaks, the current general approach, detected a majority of cases of gastroenteritis. However, if policymakers are to estimate the burden of infectious gastroenteritis in this setting using only routine outbreak surveillance data and not accounting for non-outbreak cases, this study implies that the total burden will be underestimated.

Keywords: epidemiology; gastroenteritis; norovirus; outbreaks; surveillance; viral gastroenteritis.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Disease Outbreaks / statistics & numerical data
  • England / epidemiology
  • Female
  • Gastroenteritis / epidemiology*
  • Homes for the Aged / statistics & numerical data*
  • Humans
  • Incidence
  • Male
  • Nursing Homes / statistics & numerical data*
  • Prospective Studies