29-Norlupane-1 β-hydroxy-3,20-dione, a new norlupane triterpenoid from the twigs and leaves of Phyllanthus acidus

Nat Prod Res. 2021 Oct;35(20):3384-3389. doi: 10.1080/14786419.2019.1700252. Epub 2019 Dec 9.

Abstract

A new norlupane triterpenoid, 29-norlupane-1β-hydroxy-3,20-dione (1), along with ten known compounds, 29-norlup-1-ene-3,20-dione (2), phyllanthol (3), phyllanthone (4), glochidone (5), lupeol (6), lupeone (7), 4-hydroxybenzoic acid (8), 4-hydroxybenzaldehyde (9), phyllane A (10) and methyl β-orsellinate (11) were isolated the twigs and leaves of Phyllanthus acidus. The structure of 1 was identified by interpretation of their spectroscopic data and comparison with those reported in the literature. In addition, all isolated compounds 1-11 were evaluated for their antioxidant activity.

Keywords: 29-norlupane-1β-hydroxy-3,20-dione; Phyllanthaceae; Phyllanthus acidus; antioxidant activity; norlupane triterpenoid.

MeSH terms

  • Antioxidants
  • Phyllanthus*
  • Plant Extracts
  • Plant Leaves
  • Triterpenes*

Substances

  • Antioxidants
  • Plant Extracts
  • Triterpenes