Purpose of review: We seek to provide a summary of the recent advances in juvenile dermatomyositis (JDM) that are moving the field toward precision care and personalized medicine for this uncommon condition.
Recent findings: There has been a recent international focus on developing uniform classification, disease monitoring, and treatment for juvenile dermatomyositis. In addition, there has been a steady development of translational studies to determine the genetic determinants, transcriptomic profiles, and immune cell phenotypes in JDM. Recent work toward standardization of disease classification, monitoring, and assessments together with advances in science, technology, and computing will facilitate the advancement toward true precision and personalized medicine in juvenile dermatomyositis in the near future.
Keywords: Idiopathic inflammatory myopathies; Juvenile dermatomyositis; Precision medicine; Translational research.