Orthotopic editing of T-cell receptors

Nat Biomed Eng. 2019 Dec;3(12):949-950. doi: 10.1038/s41551-019-0490-4.

Authors

Dian Kortleve¹, Dora Hammerl¹, Reno Debets²

Affiliations

¹ Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC-Cancer Institute, Rotterdam, The Netherlands.
² Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC-Cancer Institute, Rotterdam, The Netherlands. j.debets@erasmusmc.nl.

PMID: 31811268
DOI: 10.1038/s41551-019-0490-4

No abstract available

MeSH terms

Antigens, Neoplasm
CRISPR-Cas Systems
Cell Engineering
Gene Editing*
Gene Knockout Techniques
Gene Rearrangement, T-Lymphocyte
Humans
Membrane Proteins
Orthopedic Procedures
Receptors, Antigen, T-Cell / genetics*
Receptors, Antigen, T-Cell, alpha-beta / genetics

Substances

Antigens, Neoplasm
CTAG1B protein, human
Membrane Proteins
Receptors, Antigen, T-Cell
Receptors, Antigen, T-Cell, alpha-beta