Recent advances in developing disease resistance in plants

Anuj Sharma; Jeffrey B Jones; Frank F White

doi:10.12688/f1000research.20179.1

Recent advances in developing disease resistance in plants

F1000Res. 2019 Nov 19:8:F1000 Faculty Rev-1934. doi: 10.12688/f1000research.20179.1. eCollection 2019.

Authors

Anuj Sharma¹, Jeffrey B Jones¹, Frank F White¹

Affiliation

¹ Department of Plant Pathology, University of Florida, Gainesville, FL, USA.

Abstract

Approaches to manipulating disease resistance in plants is expanding exponentially due to advances in our understanding of plant defense mechanisms and new tools for manipulating the plant genome. The application of effective strategies is only limited now by adoption of rapid classical genetic techniques and the acceptance of genetically engineered traits for some problems. The use of genome editing and cis-genetics, where possible, may facilitate applications that otherwise require considerable time or genetic engineering, depending on settling legal definitions of the products. Nonetheless, the variety of approaches to developing disease resistance has never been greater.

Keywords: R genes; disease resistance; genome editing.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Disease Resistance*
Gene Editing*
Genetic Engineering
Genome, Plant*
Humans
Plants, Genetically Modified

Grants and funding

FFW gratefully acknowledge funding, in part, from the Bill and Melinda Gates Foundation to Heinrich Heine University, Düsseldorf, and subaward to University of Florida and the National Science Foundation (1741090). Any opinions expressed in the manuscript are the opinions of the authors and do not represent positions of the foundations or agencies.