Functional properties of chitosan films modified by snail mucus extract

Int J Biol Macromol. 2020 Jan 15:143:126-135. doi: 10.1016/j.ijbiomac.2019.11.230. Epub 2019 Dec 2.

Abstract

Snail mucus is an attractive natural substance, which is increasingly used in cosmetic creams and syrups thanks to its emollient, moisturizing, protective and reparative properties. The aim of the present study was to explore the physicochemical properties of chitosan-based films added with snail mucus extracted from Helix Aspersa Muller. To this aim, chitosan films at different content of snail mucus were fabricated by simple solvent casting technique. The results of X-ray diffraction analyses, tensile mechanical tests, Infrared spectroscopy and thermogravimetry demonstrated that snail mucus addition strongly modifies the properties of chitosan films. In particular, it acted like a plasticizer enhancing films extensibility up to ten times and strongly improving their water barrier and bioadhesion properties, with a trend depending on Snail mucus content. Furthermore, it provides the films with antibacterial properties and enhanced cytocompatibility, yielding materials with tailored properties for specific requirements.

Keywords: Adhesive properties; Chitosan films; Snail mucus.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Cell Line
  • Cell Survival / drug effects
  • Chemical Phenomena
  • Chitosan / chemistry*
  • Mucus / chemistry*
  • Snails / chemistry*
  • Spectrum Analysis
  • Steam
  • Thermogravimetry

Substances

  • Anti-Bacterial Agents
  • Steam
  • Chitosan