TREK for High-Speed and High-Frequency Conduction through the Axon

Pablo Ávalos Prado; Guillaume Sandoz

doi:10.1016/j.neuron.2019.11.015

TREK for High-Speed and High-Frequency Conduction through the Axon

Neuron. 2019 Dec 4;104(5):831-833. doi: 10.1016/j.neuron.2019.11.015.

Authors

Pablo Ávalos Prado¹, Guillaume Sandoz²

Affiliations

¹ Université Cote d'Azur, CNRS, INSERM, iBV, Nice, France; Laboratories of Excellence, Ion Channel Science and Therapeutics, Nice, France.
² Université Cote d'Azur, CNRS, INSERM, iBV, Nice, France; Laboratories of Excellence, Ion Channel Science and Therapeutics, Nice, France. Electronic address: sandoz@unice.fr.

PMID: 31805261
DOI: 10.1016/j.neuron.2019.11.015

Abstract

In this issue of Neuron, Kanda et al. (2019) find that the two-pore domain potassium channels TRAAK and TREK1 drive axonal action potential repolarization for high-speed and high-frequency nervous impulses in mammalian myelinated nerves.

Publication types

Comment

MeSH terms

Action Potentials
Animals
Axons
Potassium Channels, Tandem Pore Domain*
Ranvier's Nodes*

Substances

Potassium Channels, Tandem Pore Domain
potassium channel protein TREK-1